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Reactive oxygen species (ROS) may directly alter vascular function or cause changes in vascular tone by several mechanisms including altered nitric oxide (NO) bioavailability or signaling

Connecting the Dots: from free radical lipid autoxidation to cell pathology and disease

Some of the findings include the following: In a 2022 trial, subjects taking 1,000mg of urolithin A exhibited clinically meaningful improvements in their aerobic endurance and physical performance when compared to subjects who took either 500mg or a placebo.5 A separate 2022 trial examined the effects of 1,000mg urolithin A versus placebo in older adults after four months of daily supplementation